Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 2.907


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA6chr7_-_271538920.601.5e-02Click!
HOXA7chr7_-_271626880.467.0e-02Click!
HOXB7chr17_-_44042924-0.146.1e-01Click!
HOXB6chr17_-_44037332-0.126.5e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_122722674 8.781 NM_005328
HAS2
hyaluronan synthase 2
chr11_+_101488380 8.105 NM_001195045
YAP1
Yes-associated protein 1
chr3_-_55489973 6.243 WNT5A
wingless-type MMTV integration site family, member 5A
chr10_-_21847126 6.242


chr1_+_168898898 5.950 PRRX1
paired related homeobox 1
chr7_-_27149750 5.371 NM_019102
HOXA5
homeobox A5
chr7_-_41709191 5.320 NM_002192
INHBA
inhibin, beta A
chr10_+_24795446 5.198 KIAA1217
KIAA1217
chr7_-_83662152 5.124 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr10_+_24795465 5.043 KIAA1217
KIAA1217
chr21_-_34820916 4.746 NM_203418
RCAN1
regulator of calcineurin 1
chr14_+_51025604 4.746 NM_001042481
FRMD6
FERM domain containing 6
chr9_-_116920232 4.461 NM_002160
TNC
tenascin C
chr7_+_134226727 4.399 CALD1
caldesmon 1
chr10_+_69539255 4.267 NM_032578
MYPN
myopalladin
chr7_-_27108826 4.262 NM_006735
HOXA2
homeobox A2
chr2_-_164300758 4.260 NM_018086
FIGN
fidgetin
chr18_-_44723116 4.175 NM_001190823
SMAD7
SMAD family member 7
chr2_+_66516196 4.014 MEIS1
Meis homeobox 1
chr18_+_30544193 3.950 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr3_-_64186151 3.941 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr3_-_11585264 3.873 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr16_+_85169615 3.811 NM_005250
FOXL1
forkhead box L1
chr20_+_19903778 3.792 RIN2
Ras and Rab interactor 2
chr3_-_115825742 3.696 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_27604656 3.692 WASF2
WAS protein family, member 2
chr7_-_5429702 3.600 NM_001080495
TNRC18
trinucleotide repeat containing 18
chr10_-_33663305 3.580 NRP1
neuropilin 1
chr9_+_108665168 3.550 NM_021224
ZNF462
zinc finger protein 462
chr3_-_115960807 3.523 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr7_-_27171600 3.510 HOXA9
homeobox A9
chr3_-_188946168 3.489 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr1_-_20682541 3.482


chr12_-_88270128 3.405 DUSP6
dual specificity phosphatase 6
chr12_-_88270375 3.404 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr18_+_30812205 3.402 NM_001143827
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr6_+_21701942 3.375 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr10_-_29963906 3.344 NM_021738
SVIL
supervillin
chr9_+_674193 3.341


chr5_+_59819761 3.341 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr7_-_27171648 3.281 HOXA9
homeobox A9
chr8_-_49996353 3.248 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr12_-_88270369 3.200 DUSP6
dual specificity phosphatase 6
chr2_+_33213111 3.195 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr12_+_88268845 3.177 LOC100131490
hypothetical LOC100131490
chr2_-_200033445 3.139 SATB2
SATB homeobox 2
chr16_+_7322751 3.122 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr7_+_134226690 3.114 NM_033139
NM_033140
CALD1

caldesmon 1

chr15_-_31147376 3.091 NM_001103184
FMN1
formin 1
chr5_+_36642424 3.026 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_150578148 2.927 TM4SF1
transmembrane 4 L six family member 1
chr5_-_59819642 2.922 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_112513379 2.849 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr7_-_27171673 2.843 NM_152739
HOXA9
homeobox A9
chr6_+_136214495 2.837 NM_018945
PDE7B
phosphodiesterase 7B
chr20_-_10602139 2.835 JAG1
jagged 1
chr3_-_150578207 2.816 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr11_-_85107569 2.807 NM_206929
SYTL2
synaptotagmin-like 2
chr3_-_150578103 2.762 TM4SF1
transmembrane 4 L six family member 1
chr17_-_44026321 2.675 HOXB5
homeobox B5
chr10_-_92671005 2.663 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr12_+_79625538 2.653 NM_002469
MYF6
myogenic factor 6 (herculin)
chr2_+_170074457 2.645 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr4_+_81325447 2.645 NM_020226
PRDM8
PR domain containing 8
chr13_+_100902942 2.607 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_-_44026042 2.596 NM_002147
HOXB5
homeobox B5
chr9_+_117955890 2.536 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr4_-_87989291 2.530 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr13_-_101852028 2.527 NM_175929
FGF14
fibroblast growth factor 14
chr1_+_46151845 2.523 MAST2
microtubule associated serine/threonine kinase 2
chr3_-_21767819 2.519 NM_024697
ZNF385D
zinc finger protein 385D
chr21_+_29439768 2.512 C21orf7
chromosome 21 open reading frame 7
chr6_-_116488458 2.510 NM_002031
FRK
fyn-related kinase
chr5_+_36642213 2.490 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr10_+_86174665 2.490 FAM190B
family with sequence similarity 190, member B
chr15_+_55298908 2.488 NM_207040
TCF12
transcription factor 12
chr20_-_10602429 2.447 NM_000214
JAG1
jagged 1
chr1_-_85816520 2.444 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_-_152744022 2.434 SYNE1
spectrin repeat containing, nuclear envelope 1
chr10_+_111755715 2.432 NM_019903
ADD3
adducin 3 (gamma)
chr2_+_66516020 2.429 NM_002398
MEIS1
Meis homeobox 1
chr7_+_134114912 2.419 CALD1
caldesmon 1
chr2_-_151052391 2.399 NM_005168
RND3
Rho family GTPase 3
chr5_+_174084137 2.387 NM_002449
MSX2
msh homeobox 2
chr21_+_39117064 2.382 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr22_-_34566210 2.348 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr10_-_29963847 2.335


chr3_-_55490401 2.334 WNT5A
wingless-type MMTV integration site family, member 5A
chr3_+_158637273 2.297 NM_002852
PTX3
pentraxin 3, long
chr2_-_160764819 2.285 NM_000888
ITGB6
integrin, beta 6
chr14_+_85069217 2.272


chr4_+_183302105 2.252 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr11_-_85108030 2.225 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr21_-_35181956 2.204 RUNX1
runt-related transcription factor 1
chr7_+_134114701 2.200 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr3_+_161040439 2.185 SCHIP1
schwannomin interacting protein 1
chr22_-_34566276 2.167 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr8_+_77756077 2.163 ZFHX4
zinc finger homeobox 4
chr3_-_55490442 2.156 WNT5A
wingless-type MMTV integration site family, member 5A
chr6_+_144649142 2.154 UTRN
utrophin
chr3_-_64647325 2.144 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr7_-_27153892 2.134 NM_024014
HOXA6
homeobox A6
chr6_-_138862273 2.110


chr12_-_28016182 2.105 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr19_+_12995782 2.090 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_+_69998064 2.088 NM_198177
MITF
microphthalmia-associated transcription factor
chr4_+_160408447 2.082 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr6_-_138935359 2.080 NM_020464
NHSL1
NHS-like 1
chrX_-_19598912 2.078 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr11_-_128567302 2.067 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr12_+_52696908 2.060 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr17_+_36515166 2.033 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr4_-_152366970 2.025 NM_001009555
NM_001128923
SH3D19

SH3 domain containing 19

chrX_+_85404626 2.012 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr5_+_66160359 2.011 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_-_150578023 2.010 TM4SF1
transmembrane 4 L six family member 1
chr14_-_60185659 2.007 NM_005982
SIX1
SIX homeobox 1
chr20_-_14266200 1.988 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr3_+_69895310 1.983 NM_001184967
MITF
microphthalmia-associated transcription factor
chr9_-_14076901 1.980 NFIB
nuclear factor I/B
chr8_+_77756061 1.976 NM_024721
ZFHX4
zinc finger homeobox 4
chr5_+_155686333 1.975 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr1_-_191422346 1.950 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_-_207738858 1.934 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_+_52697160 1.916 HOXC5
HOXC6
homeobox C5
homeobox C6
chr2_+_66519949 1.905 MEIS1
Meis homeobox 1
chr16_-_71650034 1.904 NM_001164766
ZFHX3
zinc finger homeobox 3
chr22_-_34566367 1.900 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr6_-_56615544 1.880 NM_001723
NM_015548
DST

dystonin

chr3_-_110155237 1.879 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr11_-_56951628 1.871 NM_017611
SLC43A3
solute carrier family 43, member 3
chr12_-_88269884 1.844 DUSP6
dual specificity phosphatase 6
chr12_-_89922875 1.836 EPYC
epiphycan
chr15_+_60838053 1.835 TLN2
talin 2
chr7_-_27120015 1.823 HOXA3
homeobox A3
chr2_-_98646367 1.817 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr9_+_102380156 1.797 NM_001018116
MURC
muscle-related coiled-coil protein
chr7_-_107667728 1.790 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr18_+_3437607 1.787 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr7_-_27136876 1.784 NM_002141
HOXA4
homeobox A4
chr11_+_34599227 1.783 EHF
ets homologous factor
chr18_+_27281729 1.779 NM_001944
DSG3
desmoglein 3
chr7_+_134114957 1.774 CALD1
caldesmon 1
chr11_+_34599163 1.767 NM_012153
EHF
ets homologous factor
chr4_-_141293572 1.764 MAML3
mastermind-like 3 (Drosophila)
chr3_-_11598829 1.756 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr21_-_35343065 1.749 RUNX1
runt-related transcription factor 1
chr6_-_101018271 1.744 NM_005068
SIM1
single-minded homolog 1 (Drosophila)
chr3_-_139315011 1.706 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr3_-_188945921 1.702 BCL6
B-cell CLL/lymphoma 6
chr9_+_12764988 1.698 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr15_-_53996597 1.698 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr8_+_70541631 1.684 SULF1
sulfatase 1
chr12_+_118100977 1.677 NM_014365
HSPB8
heat shock 22kDa protein 8
chr13_-_43908937 1.675 TSC22D1
TSC22 domain family, member 1
chr11_+_131285747 1.659 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chrX_+_135106578 1.654 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr6_-_10520264 1.647 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_-_15593074 1.646 NM_020665
TMEM27
transmembrane protein 27
chr4_+_3341521 1.644 NM_198227
RGS12
regulator of G-protein signaling 12
chr12_-_16321885 1.635 NM_001170798
SLC15A5
solute carrier family 15, member 5
chr5_-_1935764 1.633 NM_016358
IRX4
iroquois homeobox 4
chr7_-_112514990 1.613 GPR85
G protein-coupled receptor 85
chr1_+_67923331 1.608 NM_001924
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr14_+_99555471 1.601 EVL
Enah/Vasp-like
chr4_+_54790020 1.597 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr8_-_10550026 1.590 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr3_+_25445071 1.582 RARB
retinoic acid receptor, beta
chr2_-_189752575 1.560 NM_000393
COL5A2
collagen, type V, alpha 2
chr16_-_30983909 1.557 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr8_-_93176819 1.547 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_157877146 1.538 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr10_+_52420936 1.533 NM_001098512
PRKG1
protein kinase, cGMP-dependent, type I
chr10_-_76831142 1.529 ZNF503
zinc finger protein 503
chr2_-_190635566 1.528 NM_005259
MSTN
myostatin
chr16_+_24696069 1.523 TNRC6A
trinucleotide repeat containing 6A
chr2_-_162808123 1.522 NM_004460
FAP
fibroblast activation protein, alpha
chr8_-_93176618 1.505 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr16_+_81218142 1.497 CDH13
cadherin 13, H-cadherin (heart)
chr12_-_89922888 1.488 NM_004950
EPYC
epiphycan
chr4_+_74488947 1.483 ALB
albumin
chr22_-_28972683 1.477 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr1_+_213245507 1.470 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr5_-_59100091 1.461 PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_-_116434364 1.460 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr3_-_71262426 1.457 FOXP1
forkhead box P1
chr8_-_13416554 1.457 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr10_-_92670764 1.436 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr4_+_54790190 1.436 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr6_+_130381408 1.434 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr5_+_92944680 1.431 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr12_+_40117751 1.429 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr12_-_13139848 1.425 NM_031289
NM_153823
GSG1

germ cell associated 1

chr7_-_112515035 1.421 GPR85
G protein-coupled receptor 85
chr11_-_85115105 1.417 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr6_-_10523424 1.398 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_-_10520592 1.396 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr5_-_56814310 1.393 NM_001017992
ACTBL2
actin, beta-like 2
chr9_-_14304036 1.393 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chrX_+_135079461 1.390 NM_001167819
FHL1
four and a half LIM domains 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 8.42e-37 GO:0032501 multicellular organismal process
1.42 3.03e-24 GO:0048731 system development
1.37 1.42e-23 GO:0007275 multicellular organismal development
1.37 4.57e-22 GO:0048856 anatomical structure development
1.33 1.35e-21 GO:0032502 developmental process
1.47 1.39e-16 GO:0003008 system process
1.49 2.02e-15 GO:0009653 anatomical structure morphogenesis
1.18 6.00e-13 GO:0050896 response to stimulus
1.45 1.29e-12 GO:0007399 nervous system development
1.45 1.59e-11 GO:0050877 neurological system process
1.59 1.82e-11 GO:0007600 sensory perception
2.55 1.86e-11 GO:0007156 homophilic cell adhesion
1.38 2.49e-11 GO:0048513 organ development
1.49 4.23e-09 GO:0009605 response to external stimulus
1.52 6.94e-09 GO:0009888 tissue development
1.71 8.80e-09 GO:0007606 sensory perception of chemical stimulus
1.32 8.91e-09 GO:0030154 cell differentiation
1.50 1.87e-08 GO:0022008 neurogenesis
1.50 4.71e-08 GO:0048699 generation of neurons
1.87 7.58e-08 GO:0016337 cell-cell adhesion
1.72 8.28e-08 GO:0007608 sensory perception of smell
1.30 8.59e-08 GO:0048869 cellular developmental process
1.82 2.52e-07 GO:0001501 skeletal system development
2.62 8.51e-07 GO:0048706 embryonic skeletal system development
1.49 1.84e-06 GO:0007155 cell adhesion
1.49 1.84e-06 GO:0022610 biological adhesion
1.51 2.01e-06 GO:0030182 neuron differentiation
1.49 2.18e-06 GO:2000026 regulation of multicellular organismal development
1.51 3.11e-06 GO:0009790 embryo development
1.43 4.44e-06 GO:0048468 cell development
1.60 5.62e-06 GO:0000904 cell morphogenesis involved in differentiation
1.49 1.57e-05 GO:0045595 regulation of cell differentiation
1.58 1.74e-05 GO:0031175 neuron projection development
1.40 1.92e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.72 2.59e-05 GO:0060284 regulation of cell development
1.41 3.41e-05 GO:0050793 regulation of developmental process
1.70 3.52e-05 GO:0007411 axon guidance
1.62 3.66e-05 GO:0007409 axonogenesis
1.59 4.48e-05 GO:0048812 neuron projection morphogenesis
1.52 4.58e-05 GO:0048666 neuron development
1.41 5.29e-05 GO:0040011 locomotion
1.77 5.99e-05 GO:0001568 blood vessel development
1.65 6.24e-05 GO:0043009 chordate embryonic development
1.74 6.25e-05 GO:0001944 vasculature development
1.64 6.35e-05 GO:0009792 embryo development ending in birth or egg hatching
1.50 6.53e-05 GO:0009887 organ morphogenesis
1.50 8.75e-05 GO:0000902 cell morphogenesis
1.48 9.76e-05 GO:0030030 cell projection organization
1.58 1.00e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.57 1.90e-04 GO:0032583 regulation of gene-specific transcription
1.43 2.34e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.52 4.27e-04 GO:0048858 cell projection morphogenesis
1.52 6.16e-04 GO:0072358 cardiovascular system development
1.52 6.16e-04 GO:0072359 circulatory system development
1.43 6.66e-04 GO:0010628 positive regulation of gene expression
1.50 7.49e-04 GO:0032990 cell part morphogenesis
1.45 8.56e-04 GO:0032989 cellular component morphogenesis
1.59 9.20e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.16 9.67e-04 GO:0023052 signaling
1.73 1.24e-03 GO:0003002 regionalization
1.62 1.41e-03 GO:0051093 negative regulation of developmental process
1.76 1.47e-03 GO:0048514 blood vessel morphogenesis
1.35 1.53e-03 GO:0042127 regulation of cell proliferation
1.48 1.93e-03 GO:0006935 chemotaxis
1.48 1.93e-03 GO:0042330 taxis
1.67 2.64e-03 GO:0045596 negative regulation of cell differentiation
1.43 2.80e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.63 3.04e-03 GO:0031667 response to nutrient levels
1.61 3.15e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.64 4.06e-03 GO:0061061 muscle structure development
2.44 4.31e-03 GO:0048634 regulation of muscle organ development
2.44 4.31e-03 GO:0048704 embryonic skeletal system morphogenesis
1.59 4.47e-03 GO:0009991 response to extracellular stimulus
1.57 5.31e-03 GO:0007389 pattern specification process
1.21 6.11e-03 GO:0048523 negative regulation of cellular process
1.45 6.29e-03 GO:0008284 positive regulation of cell proliferation
1.76 6.55e-03 GO:0048732 gland development
1.75 6.90e-03 GO:0007584 response to nutrient
2.44 6.92e-03 GO:0016202 regulation of striated muscle tissue development
1.35 7.46e-03 GO:0009891 positive regulation of biosynthetic process
1.35 7.52e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.20 8.91e-03 GO:0048519 negative regulation of biological process
1.80 1.03e-02 GO:0001525 angiogenesis
1.27 1.15e-02 GO:0051239 regulation of multicellular organismal process
1.46 1.17e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.81 1.21e-02 GO:0009952 anterior/posterior pattern formation
1.81 1.94e-02 GO:0043062 extracellular structure organization
1.15 1.99e-02 GO:0007165 signal transduction
1.35 2.13e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.08 2.28e-02 GO:0065007 biological regulation
2.18 2.46e-02 GO:0022612 gland morphogenesis
1.38 2.51e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.13 2.67e-02 GO:0051716 cellular response to stimulus
2.74 2.67e-02 GO:0071363 cellular response to growth factor stimulus
1.34 2.99e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.86 3.08e-02 GO:0048705 skeletal system morphogenesis
1.50 3.50e-02 GO:0048598 embryonic morphogenesis
3.22 3.76e-02 GO:0002053 positive regulation of mesenchymal cell proliferation
1.36 3.79e-02 GO:0051254 positive regulation of RNA metabolic process
1.08 3.88e-02 GO:0050789 regulation of biological process
2.38 4.40e-02 GO:0070848 response to growth factor stimulus
1.44 4.53e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.76 4.74e-02 GO:0048562 embryonic organ morphogenesis
1.60 4.76e-02 GO:0050767 regulation of neurogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 1.98e-16 GO:0005886 plasma membrane
1.26 2.98e-16 GO:0071944 cell periphery
1.31 2.66e-09 GO:0005576 extracellular region
1.42 6.02e-08 GO:0044421 extracellular region part
1.74 6.94e-07 GO:0005578 proteinaceous extracellular matrix
1.62 9.17e-06 GO:0031012 extracellular matrix
1.39 7.47e-05 GO:0005615 extracellular space
1.22 8.41e-05 GO:0044459 plasma membrane part
2.06 1.54e-04 GO:0044420 extracellular matrix part
1.40 1.23e-03 GO:0030054 cell junction
1.92 2.65e-03 GO:0030016 myofibril
1.85 6.25e-03 GO:0043292 contractile fiber
1.88 7.76e-03 GO:0044449 contractile fiber part
1.08 1.01e-02 GO:0016020 membrane
2.53 2.77e-02 GO:0005581 collagen
2.24 3.13e-02 GO:0031983 vesicle lumen
1.63 4.91e-02 GO:0005882 intermediate filament

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.54 2.02e-10 GO:0004930 G-protein coupled receptor activity
1.79 1.01e-09 GO:0004984 olfactory receptor activity
1.53 1.33e-07 GO:0005509 calcium ion binding
1.37 1.95e-07 GO:0004888 transmembrane receptor activity
1.51 4.65e-07 GO:0043565 sequence-specific DNA binding
1.30 7.84e-07 GO:0004872 receptor activity
1.26 5.07e-06 GO:0004871 signal transducer activity
1.26 5.07e-06 GO:0060089 molecular transducer activity
1.35 8.95e-05 GO:0001071 nucleic acid binding transcription factor activity
1.35 8.95e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.62 1.60e-04 GO:0042562 hormone binding
1.88 3.04e-04 GO:0008083 growth factor activity
1.32 6.17e-04 GO:0005102 receptor binding
1.32 7.27e-04 GO:0030528 transcription regulator activity
1.73 1.17e-03 GO:0000975 regulatory region DNA binding
1.73 1.17e-03 GO:0001067 regulatory region nucleic acid binding
1.73 1.17e-03 GO:0044212 transcription regulatory region DNA binding
1.72 2.32e-03 GO:0010843 promoter binding
2.34 1.04e-02 GO:0004879 ligand-dependent nuclear receptor activity
2.38 1.10e-02 GO:0003707 steroid hormone receptor activity
1.85 2.72e-02 GO:0008201 heparin binding